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ChemicalBook CAS DataBase List 4-Bromo-2,3,5-trifluoropyridine
851178-96-6

4-Bromo-2,3,5-trifluoropyridine synthesis

4synthesis methods
-

Yield:851178-96-6 78%

Reaction Conditions:

Stage #1: 2,3,5‐trifluoropyridinewith n-butyllithium in tetrahydrofuran;hexane at -75; for 2 h;
Stage #2: with bromine at -75; for 1 h;

References:

Bobbio, Carla;Rausis, Thierry;Schlosser, Manfred [Chemistry - A European Journal,2005,vol. 11,# 6,p. 1903 - 1910]

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