4-Chlorobenzyl bromide synthesis
- Product Name:4-Chlorobenzyl bromide
- CAS Number:622-95-7
- Molecular formula:C7H6BrCl
- Molecular Weight:205.48
Yield:622-95-7 86% ，104-83-6 6%
Reaction Conditions:
with tetra-N-butylammonium tribromide;1,3-dichloro-[1,3,5]triazinane-2,4,6-trione in dichloromethane at 20; for 2 h;Photolysis;Time;Reagent/catalyst;Concentration;
Steps:
13 Halo-de-carboxylation of 4-chlorophenylacetic acid chloroisocyanurate/brominating agent
General procedure: A mixture of 4-chlorophenylacetic acid (1 mmol), chloroisocyanurate, brominating agent and solvent (6 mL) was stirred under fluorescent room light irradiation (FL). An aliquot of the reaction mixture washed with 1 M aq Na2S03, dried over Na2S04, and filtered through short neutral silica gel pad. The yields of 4-chlorobenzyl bromide and chloride, and 4-chlorobenzal bromide were determined by gas chromatography (GC) using 1,2,4-trichlorobenzene as internal standard. The results are presented in Table 9
References:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED;GANDELMAN, Mark;NISNEVICH, Gennady A.;KULBITSKI, Kseniya;ARTARYAN, Alexander WO2017/60906, 2017, A1 Location in patent:Paragraph 00163
873-76-7
353 suppliers
$6.00/10g
622-95-7
238 suppliers
$6.00/1g
104-83-6
384 suppliers
$15.00/50g
622-95-7
238 suppliers
$6.00/1g
1878-66-6
452 suppliers
$6.00/25g
622-95-7
238 suppliers
$6.00/1g
106-43-4
360 suppliers
$14.00/5g
622-95-7
238 suppliers
$6.00/1g