4'-PHENOXY-2,2,2-TRIFLUOROACETOPHENONE synthesis
- Product Name:4'-PHENOXY-2,2,2-TRIFLUOROACETOPHENONE
- CAS Number:70783-32-3
- Molecular formula:C14H9F3O2
- Molecular Weight:266.22
2215-77-2
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$8.00/5g
81290-20-2
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$13.00/1g
70783-32-3
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$254.00/1g
Yield:70783-32-3 85 %
Reaction Conditions:
with dmap;cesium fluoride;trifluoroacetic anhydride at 120;Inert atmosphere;
Steps:
8 Preparation Example 8
Add 0.2mmol (1 equivalent) of 4-phenoxybenzoic acid, TMSCF30.6mmol, 2.0 equivalents of trifluoroacetic anhydride, 2.5 equivalents of DMAP, 2.5 equivalents of CsF, and 2.0ml of anisole in a 25mL reaction tube.solvent, and reacted at 120° C. for 15 hours under a nitrogen atmosphere.After the reaction, the target compound trifluoromethyl ketones were separated by column chromatography to obtain a yellow liquid with a yield of 85%.
References:
CN115536510,2022,A Location in patent:Paragraph 0031-0032
16184-89-7
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139-02-6
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$34.00/5g
70783-32-3
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$254.00/1g
655-32-3
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$9.00/1g
108-95-2
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$14.00/25g
70783-32-3
30 suppliers
$254.00/1g
101-84-8
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$5.00/25g
96254-05-6
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$312.00/10ml
70783-32-3
30 suppliers
$254.00/1g