5-Chloro-2-fluoroaniline synthesis
- Product Name:5-Chloro-2-fluoroaniline
- CAS Number:2106-05-0
- Molecular formula:C6H5ClFN
- Molecular Weight:145.56
Yield:-
Reaction Conditions:
with 5%-palladium/activated carbon;hydrazine hydrate in methanol at 80; for 0.0833333 h;Overall yield = 25 %;
Steps:
General Procedures; Method A:
General procedure: To a mixture ofhalogenated nitroarene (1 mmol), Pd/C(5%), and MeOH (5mL) was added NH2NH2·H2O (10 mmol), and the resultingsolution was heated at 80 °C reflux condition for 5 min. Thenthe mixture was filtered and concentrated in vacuo. Thecrude material was purified by flash column
References:
Li, Fang;Frett, Brendan;Li, Hong-Yu [Synlett,2014,vol. 25,# 10,art. no. ST-2014-R0200-L,p. 1403 - 1408]
345-18-6
202 suppliers
$7.00/5g
2106-05-0
227 suppliers
$8.00/5g