9-Anthracenemethanol synthesis
- Product Name:9-Anthracenemethanol
- CAS Number:1468-95-7
- Molecular formula:C15H12O
- Molecular Weight:208.26
642-31-9
345 suppliers
$10.00/5g
1468-95-7
365 suppliers
$8.00/5g
Yield:1468-95-7 99%
Reaction Conditions:
with sodium tetrahydroborate in ethanol at 20; for 0.5 h;
Steps:
Anthracen-9-yl-methanol
General procedure: 9-Anthraldehyde (1; 206 mg, 1.0 mmol) wassuspended in ethanol (3.0 mL). To the suspension was added sodium borohydride(38 mg, 1.0 mmol). After stirring for 30 min at rt, the reaction mixture was quenched with water (2 mL). The aqueous phase was extracted with ether (5 mL). The organicextract was dried over anhydrous Na2SO4 and concentrated to give the crude alcohol, which waspurified by flash column chromatography (silica gel 10 g, hexanes/ethyl acetate = 80/20) to give thealcohol 5 (206 mg, 99%) as a pale yellow solid. Registry number 1468-95-7; Rf = 0.27(hexane:AcOEt = 80:20); 1H NMR (CDCl3, 300 MHz) δ = 1.80 (brs, 1H, -OH), 5.62 (s, 2H, -CH2-),7.38-7.64 (m, 4H, Ar), 8.00 (d, J = 8.3 Hz, 2H, Ar), 8.38 (d, J = 8.7 Hz, 2H, Ar), 8.44 (s, 1H, H-10)
References:
Mase, Nobuyuki;Takabe, Kunihiko;Tanaka, Fujie [Tetrahedron Letters,2013,vol. 54,# 32,p. 4306 - 4308] Location in patent:supporting information
![Anthracene, 9-[[(trimethylsilyl)oxy]methyl]-](/CAS/20210305/GIF/88920-56-3.gif)
88920-56-3
0 suppliers
inquiry
1468-95-7
365 suppliers
$8.00/5g
16430-32-3
1 suppliers
inquiry
1468-95-7
365 suppliers
$8.00/5g
2417-77-8
108 suppliers
$6.00/100mg
1468-95-7
365 suppliers
$8.00/5g