Betaine synthesis
- Product Name:Betaine
- CAS Number:107-43-7
- Molecular formula:C5H11NO2
- Molecular Weight:117.15
67-48-1
795 suppliers
$9.00/1g
107-43-7
817 suppliers
$5.00/25mg
Yield:107-43-7 90.1%
Reaction Conditions:
with sodium hypochlorite;sodium chlorite;2,2,6,6-Tetramethyl-1-piperidinyloxy free radical in acetonitrile; for 10 h;Solvent;
Steps:
1 Example 1
A method for preparing a betaine in the present example comprises the steps of:A. With a reflux condenser, thermometer,Pressure-equalizing dropping funnel, magnetic stirring means and a three-necked flask was added choline chloride (139.5g, 1.0mol),Acetonitrile 1100 g and catalyst 2,2,6,6-tetramethylpiperidine nitrogen oxide (2.79 g);B. Add a solution of sodium hypochlorite (409.7 g) with a mass ratio of 10% to the mixture while stirring,Mass ratio of 10% sodium chlorite solution (1990g),After completion of the dropwise addition, the reaction was continued for 10 hours.C. After the reaction,Stirring into the amount of sodium thiosulfate solution to starch potassium iodide test paper unchanged blue,And then most of the solvent is removed by distillation,Volume concentrated to 10%Residual liquid through the ion-type macroporous adsorption resin to remove inorganic salt ions to get betaine aqueous solution,Atmospheric distillation to remove most of the water,Volume concentrated to 10%There is a solid precipitation, filtration collection of solid,Dried at 60 ° C / 10 mmHg for 6 hours,The yield of betaine was 105.4 g and the yield was about 90.1%.
References:
CN104557579,2017,B Location in patent:Paragraph 0013; 0024; 0025; 0026; 0027; 0028; 0029-0053
62-49-7
80 suppliers
$505.54/5MG
107-43-7
817 suppliers
$5.00/25mg
