一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Cabazitaxel N-3
859498-31-0

Cabazitaxel N-3 synthesis

7synthesis methods
196404-55-4 Synthesis
(4S,5R)-3-tert-butoxycarbony-2-(4-anisy)-4-phenyl-5-oxazolidinecarboxylic acid

196404-55-4
206 suppliers
$8.00/250mg

Cabazitaxel N-3

859498-31-0
12 suppliers
inquiry

-

Yield:859498-31-0 93.9 %

Reaction Conditions:

with dmap;dicyclohexyl-carbodiimide in toluene at 10 - 20;Temperature;

Steps:

1.S2-3.S2 Step S2:

Add 78g of toluene, 0.63g of 4-dimethylaminopyridine, the above 9.1g of intermediate I and 8.8g of docetic side chain acid to the reaction kettle and stir; 6.4g N,N'-dicyclohexylcarbodiimide was dissolved with 12.75g toluene and added dropwise to the reactor, and stirred for 60 minutes after adding at a controlled temperature of 10~20 °C. After the end of the reaction, add 30.2g of purified water and 27.1g of ethyl acetate to stop the reaction, stir for about 1.5 hours, centrifuge to collect the filtrate, wash with about 30.6g of 0.2mol/L dilute hydrochloric acid, stratify after standing, extract the aqueous phase with 5.4g ethyl acetate, stratify after standing, combine the organic phase, wash twice with 9% sodium chloride solution (16.5g sodium chloride solution each time), dry the organic phase with 24g anhydrous sodium sulfate, filter, and concentrate the filtrate to oil, After adding methanol and beating, 12.2g of intermediate II was obtained by filtration and drying, and the yield was 93.90%.

References:

CN115232092,2022,A Location in patent:Paragraph 0041; 0044; 0056; 0059; 0063; 0066

949459-78-3 Synthesis
Cabazitaxel Impurity 32 (Mixture of Diastereomers)

949459-78-3
22 suppliers
inquiry

Cabazitaxel N-3

859498-31-0
12 suppliers
inquiry

Cabazitaxel N-3 Related Search:

五华县| 鹤岗市| 平利县| 湛江市| 诸城市| 建平县| 晋州市| 宜兴市| 尚志市| 哈密市| 井研县| 金门县| 乡城县| 阿拉尔市| 西安市| 东辽县| 华宁县| 定州市| 神农架林区| 庆城县| 太原市| 永安市| 高邮市| 丘北县| 那曲县| 施秉县| 平遥县| 湖南省| 怀柔区| 肥东县| 玉田县| 安岳县| 抚远县| 连山| 三台县| 汝城县| 平顶山市| 广州市| 安远县| 海淀区| 青神县|