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ChemicalBook CAS DataBase List DIFLUOROMETHYLPHOSPHONIC ACID DIETHYL ESTER
1478-53-1

DIFLUOROMETHYLPHOSPHONIC ACID DIETHYL ESTER synthesis

6synthesis methods
Diethyl Difluoromethylphosphonate is prepared by the reaction of sodium diethyl phosphite with Chlorodifluoromethane in hexane (49% yield) or in THF (77% yield) or generated in situ from diethyl bromodifluoromethylphosphonate and BuLi.

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