一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Diphenhydramine
58-73-1

Diphenhydramine synthesis

13synthesis methods
Diphenhydramine, 2-diphenylmethoxy-N,N-dimethylamine (10.2.5), is synthesized by the esterification of 2-dimethylaminoethanol with benzhydrylbromide [35–37].

-

Yield:58-73-1 98%

Reaction Conditions:

with di(n-butyl)tin oxide;3-methyl-1-propylimidazolium bromide in neat (no solvent) for 8 h;Reflux;Reagent/catalyst;

Steps:

1-6 Example 5
36.8 g (0.2 mol) of diphenylmethanol and dimethylaminoethanol 53.4 g (0.6 mol) were added to a 250 mL single-mouth bottle. 2.6 g (7% of the mass of diphenylmethanol) of dibutyltin oxide andIonic liquid 1-methyl-3-n-propylimidazolium bromide 1.8 g (5% by mass of diphenylmethanol), the reaction mixture was reacted under stirring at reflux. The reaction was examined by gas chromatography to determine the extent of the reaction. After the reaction for 8 hours, the reaction was completed, and the excess dimethylaminoethanol (which can be recovered and reused) was distilled off under reduced pressure, and then the temperature was elevated to obtain 50.0 g of diphenhydramine, and the yield was 98.0%. The purity is 99.5%.

References:

Jiaxing College;Zong Qianshou;Wang Jianbo;Song Xixi;Qiu Guanyinsheng;Bao Lin;Miao Chengping;Zhang Yang CN104892435, 2016, B Location in patent:Paragraph 0023-0034

FullText

Diphenhydramine Related Search:

灵台县| 威海市| 承德县| 舟山市| 芜湖市| 勃利县| 铁岭市| 尉犁县| 曲水县| 邻水| 秭归县| 长岭县| 青河县| 惠来县| 磐安县| 普兰县| 宁化县| 丰宁| 察雅县| 嘉善县| 昆明市| 永定县| 安西县| 泗洪县| 垣曲县| 新丰县| 阳曲县| 永丰县| 治多县| 喀喇沁旗| 陕西省| 武城县| 玉溪市| 正蓝旗| 西华县| 理塘县| 裕民县| 玉龙| 天镇县| 辽阳市| 通化县|