一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Diphenhydramine
58-73-1

Diphenhydramine synthesis

13synthesis methods
Diphenhydramine, 2-diphenylmethoxy-N,N-dimethylamine (10.2.5), is synthesized by the esterification of 2-dimethylaminoethanol with benzhydrylbromide [35–37].

-

Yield:58-73-1 98%

Reaction Conditions:

with di(n-butyl)tin oxide;3-methyl-1-propylimidazolium bromide in neat (no solvent) for 8 h;Reflux;Reagent/catalyst;

Steps:

1-6 Example 5
36.8 g (0.2 mol) of diphenylmethanol and dimethylaminoethanol 53.4 g (0.6 mol) were added to a 250 mL single-mouth bottle. 2.6 g (7% of the mass of diphenylmethanol) of dibutyltin oxide andIonic liquid 1-methyl-3-n-propylimidazolium bromide 1.8 g (5% by mass of diphenylmethanol), the reaction mixture was reacted under stirring at reflux. The reaction was examined by gas chromatography to determine the extent of the reaction. After the reaction for 8 hours, the reaction was completed, and the excess dimethylaminoethanol (which can be recovered and reused) was distilled off under reduced pressure, and then the temperature was elevated to obtain 50.0 g of diphenhydramine, and the yield was 98.0%. The purity is 99.5%.

References:

Jiaxing College;Zong Qianshou;Wang Jianbo;Song Xixi;Qiu Guanyinsheng;Bao Lin;Miao Chengping;Zhang Yang CN104892435, 2016, B Location in patent:Paragraph 0023-0034

FullText

Diphenhydramine Related Search:

洛南县| 扬州市| 武隆县| 吉安县| 福安市| 兖州市| 霍林郭勒市| 娄底市| 凉山| 巴林左旗| 黄梅县| 准格尔旗| 南阳市| 江门市| 河北区| 汝阳县| 宜宾市| 浪卡子县| 泸州市| 中阳县| 汝城县| 花莲市| 建阳市| 红河县| 平阳县| 壶关县| 邢台县| 泸溪县| 靖江市| 盐城市| 来安县| 来安县| 城市| 东乌| 兴仁县| 镇坪县| 芜湖县| 琼海市| 鹿泉市| 安阳市| 昌江|