Gallamine triethiodide synthesis
1synthesis methods
- Product Name:Gallamine triethiodide
- CAS Number:65-29-2
- Molecular formula:C30H60I3N3O3
- Molecular Weight:891.53
Gallamine, 1,2,3-tris-(2-triethylaminoethoxy)benzene triiodide, is
synthesized from pyrogallol, the hydroxyl groups of which are esterified by 2-diethylaminoethylchloride
in the presence of sodium amide. The resulting 1,2,3-tris-(2-triethylaminoethoxy)
benzene is further alkylated at all three nitrogen atoms by
ethyliodide, giving gallamine.
![2,2',2''-[benzene-1,2,3-triyltri(oxy)]tris[N,N-diethylethylamine]](/CAS/GIF/153-76-4.gif)
Yield:-
Reaction Conditions:
with ethanol
References:
de Lestrange [Annales Pharmaceutiques Francaises,1948,vol. 6,p. 450]