Isonicotinic acid synthesis
- Product Name:Isonicotinic acid
- CAS Number:55-22-1
- Molecular formula:C6H5NO2
- Molecular Weight:123.11
108-89-4
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$14.00/25mL
55-22-1
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$5.00/5g
Yield:55-22-1 97%
Reaction Conditions:
with sulfuric acid;ozone;acetic acid;manganese(II) acetate at 16; for 1 h;
Steps:
9 Example 9:
Example 9: 4-Pyridinecarboxylic Acid In a 100 ml jacketed vessel, 200 ml of acetic acid, 0.05 g of manganese(II) acetate, 1.91 g of sulfuric acid and 14.1 g of 4-methylpyridine were initially charged. The mixture was cooled to 16° C. and 4.0 g of ozone were introduced within a period of 60 minutes. After completion of ozonolysis, the ozone present in the solvent was blown out using nitrogen. Analysis of the reaction mixture by means of HPLC or GC gave the following results: 4-methylpyridine: >0.1%; 4-pyridinecarboxylic acid: 97%
References:
US2003/216577,2003,A1 Location in patent:Page/Page column 4
100-43-6
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$26.19/5ml
55-22-1
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$5.00/5g
100-48-1
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$8.00/25g
55-22-1
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$5.00/5g
872-85-5
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$10.00/1g
55-22-1
638 suppliers
$5.00/5g