Itaconic acid synthesis
- Product Name:Itaconic acid
- CAS Number:97-65-4
- Molecular formula:C5H6O4
- Molecular Weight:130.1
498-24-8
114 suppliers
$80.20/10g
79-41-4
546 suppliers
$14.00/5g
498-23-7
165 suppliers
$29.82/10g
594-61-6
360 suppliers
$5.00/5g
97-65-4
588 suppliers
$5.00/25g
Yield:79-41-4 51.67 %Spectr. ，498-23-7 14.7 %Spectr. ，97-65-4 5.46 %Spectr. ，594-61-6 12.62 %Spectr.
Reaction Conditions:
with sodium hydroxide in water at 190; under 112511 Torr; for 0.241667 h;Temperature;
Steps:
40
The feed solution for the experiment was prepared by mixing together a di-carboxylic acid (either itaconic, citraconic or mesaconic acid) (65 g, 0.5 moles) and sodium hydroxide (20 g, 0.5 moles) . The two solids were then dissolved in 915 g de-ionised water to give a total feed solution weight of 1 kg. The reaction solution was then fed into the ThalesNano X- Cube Flash apparatus at the required flow rate to obtain 120, 240, 366, 480, 600 and 870 seconds residence times. Every experiment was carried out at a set pressure of 150 bar (2176 psi) . The temperature of the reactor was adjusted according to the requirements of each experiment. X-Cube Flash Operation Ensure both pump lines are attached and immersed in solvent. Set the reaction pressure to the required pressure (150 bar) . Set the reaction temperature to the required temperature. Ensure that the feed line for pump 1 is inserted into the reactant feed solution bottle. Select pump 1 and set to the required flow rate of the feed solution to achieve the desired residence time of the solution in the reactor. Start the experiment and run the pumplfor 20 minutes. After running the pump for 20 minutes start to collect the liquid sample exiting the X-cube. After sufficient reactor exit has been collected, the X- Cube will need to be flushed with water to avoid cross contamination between experimental samples. Ensure that the feed line for pump 2 is inserted into the water feed bottle. Switch the liquid feed to the reactor from that fed from pump 1 (reactant solution) to that fed from pump 2 (water) . Run the pump for 20 minutes so that no reactant solution is left in the reactor. Analysis
References:
WO2013/160703,2013,A1 Location in patent:Page/Page column 26
498-23-7
165 suppliers
$29.82/10g
97-65-4
588 suppliers
$5.00/25g
77-92-9
1785 suppliers
$5.00/10g
79-41-4
546 suppliers
$14.00/5g
498-23-7
165 suppliers
$29.82/10g
498-24-8
114 suppliers
$80.20/10g
97-65-4
588 suppliers
$5.00/25g
498-24-8
114 suppliers
$80.20/10g
79-41-4
546 suppliers
$14.00/5g
498-23-7
165 suppliers
$29.82/10g
97-65-4
588 suppliers
$5.00/25g
585-84-2
159 suppliers
$30.00/20mg
97-65-4
588 suppliers
$5.00/25g