Methyl 3-bromobenzoate synthesis
- Product Name:Methyl 3-bromobenzoate
- CAS Number:618-89-3
- Molecular formula:C8H7BrO2
- Molecular Weight:215.04
585-76-2
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$6.00/5g
618-89-3
273 suppliers
$28.00/5g
Yield:618-89-3 85%
Reaction Conditions:
with sulfuric acid in methanol;dichloromethane;ethyl acetate
Steps:
2.A Methyl 3-(2-α-L-fucopyranosyloxy)phenyl)benzoate
Part A: 3-Bromobenzoic acid (1.1 g, 5.47 mmol) was dissolved in methanol (20 ml) in a 50 ml flask. Concentrated sulfuric acid (2 drops) was added and the mixture was refluxed under nitrogen for ten hours then concentrated under reduced pressure. The residue was mixed with dichloromethane (20 ml) and saturated sodium bicarbonate solution (10 ml). The organic material was separated, dried (MgSO4) and concentrated under reduced pressure. The residue was flushed through silica gel with hexane/ethyl acetate (3:1), and concentrated which provided methyl 3-bromobenzoate (1.0 g, 85%).
References:
Texas Biotechnology Corporation US5622937, 1997, A
93-58-3
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618-89-3
273 suppliers
$28.00/5g
75-91-2
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591-17-3
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618-89-3
273 suppliers
$28.00/5g
67-56-1
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$7.29/5ml-f
15852-73-0
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618-89-3
273 suppliers
$28.00/5g