N-Methylpyrrole-2-carboxaldehyde synthesis
- Product Name:N-Methylpyrrole-2-carboxaldehyde
- CAS Number:1192-58-1
- Molecular formula:C6H7NO
- Molecular Weight:109.13
1003-29-8
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$10.00/1g
1119-97-7
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$5.00/25g
1192-58-1
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$9.00/5g
Yield:1192-58-1 46%
Reaction Conditions:
with sodium hydroxide in water;toluene for 5 h;Reflux;chemoselective reaction;
Steps:
4.2. General Procedure for the Synthesis of 1b-7b and 11b.
General procedure: A 100mL round-bottom flask was equipped with a magnetic stir bar and a reflux condenser. To xylene (10.0mL), tetradecyltrimethylammonium bromide (1.1mmol) and a heterocyclic compound (1.0mmol) were added, followed bya solution of NaOH 50% (5.0 mL). The mixture was stirred at reflux temperature for 2-18 h. After completion of thereaction, the mixture was air-jet cooled to 25 °C and TLC indicated the disappearance of the starting material. The reaction mix was treated with AcOEt (4 × 20 mL), and the organic phase separated and removed under reduced pressure. The residue was purified to analytical purity by column chromatography.
References:
González-González, Carlos A.;Vega, Juan Javier Mejía;Monroy, Ricardo García;González-Calderón, Davir;Corona-Becerril, David;Fuentes-Benítes, Aydeé;Mascarúa, Joaquín Tamariz;González-Romero, Carlos [Journal of Chemistry,2017,vol. 2017,art. no. 4586463]
96-54-8
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$5.00/1g
1192-58-1
190 suppliers
$9.00/5g
6973-60-0
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$6.00/250mg
1192-58-1
190 suppliers
$9.00/5g
