Tosyl chloride synthesis
- Product Name:Tosyl chloride
- CAS Number:98-59-9
- Molecular formula:C7H7ClO2S
- Molecular Weight:190.65
CH3C6H5+ SO2Cl2→ CH3C6H4SO2Cl + HCl
1576-35-8
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98-59-9
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$9.00/5g
Yield:98-59-9 99%
Reaction Conditions:
with N-chloro-succinimide in acetonitrile at 20; for 2 h;Reagent/catalyst;Solvent;
Steps:
4.2. General Procedure for Synthesis of Sulfonyl Chloride 3 or Sulfonyl Bromide 4
General procedure: N-Chlorosuccinimide 2a or N-bromosuccinimide 2b (0.6 mmol, 2.0 equiv) was addedto a solution of sulfonyl hydrazide 1 (0.3 mmol) in CH3CN (2 mL) in one portion. Themixture was stirred at room temperature for 2 h. The solvent was removed, and the residuewas purified by flash column chromatography (petroleum ether/ethyl acetate) to providethe corresponding sulfonyl chloride 3 or sulfonyl bromide 4.
References:
Chen, Rongxiang;Xu, Shaohong;Shen, Fumin;Xu, Canran;Wang, Kaikai;Wang, Zhanyong;Liu, Lantao [Molecules,2021,vol. 26,# 18,art. no. 5551]
657-84-1
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98-59-9
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104-15-4
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$133.00/500g
98-59-9
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106-45-6
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98-59-9
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108-88-3
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$14.00/100ml
98-59-9
619 suppliers
$9.00/5g