外觀性狀無(wú)色柱狀結(jié)晶。 微溶于水，不溶于苯和醚。

溶解性微溶于水，不溶于苯和醚。

熔點(diǎn)188-190 °C (dec.) (lit.)

熔點(diǎn)188-190 °C (dec.)(lit.)

沸點(diǎn)295.67°C (rough estimate)

密度1.5216 (rough estimate)

折射率1.6280 (estimate)

儲(chǔ)存條件Keep in dark place,Sealed in dry,Room Temperature

溶解度10g/l

酸度系數(shù)(pKa)2.43(at 25℃)

形態(tài)結(jié)晶粉末

顏色白色至淺黃米色

氣味 (Odor)odorless

水溶解性0.55 g/100 mL

Merck14,8073

檢測(cè)方法HPLC,NMR

BRN137110

InChI1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)

InChIKeyGJAWHXHKYYXBSV-UHFFFAOYSA-N

SMILESOC(=O)c1cccnc1C(O)=O

警示詞警告

WGK Germany3

WGK Germany3

RTECS號(hào)US7967250

TSCAT

REACH 注冊(cè)登記Active

危險(xiǎn)等級(jí)IRRITANT

海關(guān)編碼29333999

存儲(chǔ)類別11 - Combustible Solids

危險(xiǎn)性類別Eye Irrit. 2
STOT SE 3

毒性Focal injection of quinolinic acid into specific areas of the brain produces neuronal damage although sparing axons of passage. Similarities between the biochemical and morphological profiles of these lesions and human neuropathy seen in neurodegenerative diseases have led to the proposal that endogenous excitotoxins may play a role in such neurodegenerative disease states. Quinolinic acid is an intermediate in the kynurenine pathway of tryptophan metabolism and has been detected in the brains of several mammals including man. The neuroexcitatory action is thought to be mediated via interaction with the N-methyl-D-aspartate (NMDA) receptor of the glutamate family. No mechanism for quinolinic acid removal, nor for synaptic inactivation, has been found, and consequently accumulation of concentrations capa_x0002_ble of inducing neuronal degeneration and death may occur.