PD 166793 価格 もっと(4)

メーカー	製品番號	製品説明	CAS番號	包裝	価格	更新時間	購入
富士フイルム和光純薬株式會社(wako)	W01MAS095352	(S)-2-(4'-Bromo-[1,1'-biphenyl]-4-ylsulfonamido)-3-methylbutanoic acid	199850-67-4	250mg	￥295800	2024-03-01	購入
富士フイルム和光純薬株式會社(wako)	W01MAS095352	(S)-2-(4'-Bromo-[1,1'-biphenyl]-4-ylsulfonamido)-3-methylbutanoic acid	199850-67-4	1g	￥656900	2024-03-01	購入
富士フイルム和光純薬株式會社(wako)	W01TOC2520	PD 166793	199850-67-4	10mg	￥53000	2024-03-01	購入
富士フイルム和光純薬株式會社(wako)	W01TOC2520	PD 166793	199850-67-4	50mg	￥221000	2024-03-01	購入

PD 166793 化學(xué)特性,用途語,生産方法

使用

PD 166793 is a matrix metalloproteinase inhibitor in the treatment of inflammatory pathological occurrences involving blood pressure and the cardiac system.

一般的な説明

A cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC₅₀ = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 μM), MMP-1, -7, -9, and -14 (IC₅₀ = 6.1, 7.2, 7.9, and 0.24 μM, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes.

生物活性

Broad spectrum matrix metalloprotease (MMP) inhibitor. Displays high affinity for MMP-2, -3 and -13 (IC 50 values are 4, 7 and 8 nM respectively) and exhibits > 750-fold selectivity over MMP-1, -7 and -9. Attenuates left ventricular remodelling and dysfunction in rat model of heart failure.

PD 166793 上流と下流の製品情報

原材料

準(zhǔn)備製品

PD 166793 生産企業(yè)

名前	電話番號	電子メール	國籍	製品カタログ	優(yōu)位度
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32466	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30224	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29093	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49895	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64

199850-67-4()キーワード:

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• 199850-67-4
• PD 166793
• (S)-2-(4'-bromobiphenyl-4-ylsulfonamido)-3-methylbutanoic acid
• N-[(4'-Bromo[1,1'-biphenyl]-4-yl)sulfonyl]-L-valine
• (S)-2-(4'-Bromo-[1,1'-biphenyl]-4-ylsulfonamido)-3-methylbutanoic acid
• MMP-2/MMP-3 Inhibitor
• L-Valine, N-[(4'-bromo[1,1'-biphenyl]-4-yl)sulfonyl]-
• (2S)-2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoicaci
• PD 166793 USP/EP/BP
• PD-166793-0000
• PD-166793, 10 mM in DMSO
• MMP-2/MMP-3 Inhibitor III, PD166793