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2-Amino-6-chloro-3-nitropyridine

2-Amino-6-chloro-3-nitropyridine ??? ???
?? ??:
27048-04-0
???:
2-Amino-6-chloro-3-nitropyridine
???(??):
6-CHLORO-3-NITROPYRIDIN-2-AMINE;LABOTEST-BB LT00012599;2-Amino-6-chloro-3-nitrop...;2-amino-3-nitrochloropyridine;6-Chlor-3-nitropyridin-2-amin;2-Amino-3-nitro-6-chloropyridi;2-Amino-6-chlor-3-nitropyridin;2-Amino-6-chloro-nitro pyridne;FlupirtinemaleateintermediateI;6-Chloro-3-nitro-2-pyridinamine
CBNumber:
CB0245762
???:
C5H4ClN3O2
??? ??:
173.56
MOL ??:
27048-04-0.mol

2-Amino-6-chloro-3-nitropyridine ??

???
195-196
?? ?
339.9±37.0 °C(Predicted)
??
1.596±0.06 g/cm3(Predicted)
?? ??
Keep in dark place,Inert atmosphere,2-8°C
???
?????, DMSO ? ???
??? ??
?? ??
?? ?? (pKa)
-1.69±0.50(Predicted)
??
???
???
?? ?? ?????. ????????? ?????? ?????.
InChI
InChI=1S/C5H4ClN3O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H,(H2,7,8)
InChIKey
WERABQRUGJIMKQ-UHFFFAOYSA-N
SMILES
C1(N)=NC(Cl)=CC=C1[N+]([O-])=O
CAS ??????
27048-04-0(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 22-26-36/37/39
????(UN No.) 2811
?? ?? ?? Irritant
?? ?? 6.1
????
HS ?? 29333999
????(GHS): Skull and Crossbones (GHS06)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H312 ??? ???? ??? ?? ?? ?? - ?? ?? 4 ?? P280,P302+P352, P312, P322, P363,P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H331 ???? ??? ?? ?? ?? ?? ?? 3 ?? P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P280 ????/???/???/?????? ?????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
0
2 0

2-Amino-6-chloro-3-nitropyridine MSDS


2-Amino-6-chloro-3-nitropyridine

2-Amino-6-chloro-3-nitropyridine C??? ??, ??, ??

??

2-Amino-6-chloro-3-nitropyridine is a cytotoxic drug that has been shown to have anti-viral potency, as well as antiviral activity in an activity test. It is synthesized by reacting hydrogen tartrate with oxadiazole, and then hydrolyzing the resulting product with chloride. 2-Amino-6-chloro-3-nitropyridine has also been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in vitro and to be effective against other viruses such as type 2 influenza. This drug can bind to the viral envelope and inhibit fusion of the viral membrane with host cells by preventing the release of viral contents into the cytoplasm. The binding affinity of 2-amino 6-chloro 3 nitropyridine for chloride may be due to hydrogen bonding interactions.

??? ??

YELLOW POWDER

??

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

2-Amino-6-chloro-3-nitropyridine ?? ?? ? ???

???

?? ??


2-Amino-6-chloro-3-nitropyridine ?? ??

???( 408)?? ??
??? ?? ??? ?? ?? ? ??
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2-Amino-6-chloro-3-nitropyridine ?? ??:

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