1,3-Diphenylbenzene synthesis
- Product Name:1,3-Diphenylbenzene
- CAS Number:92-06-8
- Molecular formula:C18H14
- Molecular Weight:230.3
Yield:92-06-8 97%
Reaction Conditions:
with potassium carbonate;triphenylphosphine;palladium dichloride at 70; for 24 h;Catalytic behavior;Sealed tube;Suzuki Coupling;Reagent/catalyst;Solvent;Temperature;
Steps:
General procedure for Pd-catalyzed coupling betweenequal amount of dihaloarene and arylboronic acid
General procedure: A mixture of dihaloarene (0.4 mmol), arylboronicacid (0.4 mmol), K2CO3 (0.8 mmol), PdCl2 (7 mol %),PPh3 (15 mol %), and PEG-400 (2 mL) in a sealed tubewas stirred in air at 70°C for the desired time until completeconsumption of starting material as monitored byTLC. After that the mixture was poured into ethyl acetate,then washed with water, extracted with ethyl acetate, driedby anhydrous Na2SO4, then fi ltered and evaporated undervacuum, the residue was purifi ed by fl ash column chromatography(petroleum ether or petroleum ether/ethylacetate) to afford the corresponding coupling products
References:
Mao, Jincheng;Li, Ran;He, Yue;Yang, Xiaojiang;Wang, Dingli;Zhang, Yang [Russian Journal of Applied Chemistry,2016,vol. 89,# 4,p. 663 - 669]
