p-Terphenyl synthesis
- Product Name:p-Terphenyl
- CAS Number:92-94-4
- Molecular formula:C18H14
- Molecular Weight:230.3
Yield:92-94-4 99%
Reaction Conditions:
with potassium carbonate in water at 50; for 1.5 h;Suzuki Coupling;
Steps:
2.4 Synthesis of Biaryls 3
General procedure: In a test tube equipped with a magnetic stirrer bar, thearyl halide 1 (1 mmol) was mixed with phenyl boricacid 2 (1.2 mmol), K2CO3(2 mmol), and the Pd-catalyst(0.1mol% Pd) in 2 ml of H2Oin air. The reaction mixturewas then stirred at 50 °C for appropriate time. After completionof the reaction, the catalyst was removed by magnetand washed with ethanol and water (3 × 5 ml). The aqueouslayer was extracted with chloroform, then organic layerdried over anhydrous MgSO4.The solvent was evaporatedunder reduced pressure to give the corresponding biarylcompounds. All the products were previously reported [5,8-12] and were confirmed by the spectroscopic methodusing 1H and 13C NMR (see supporting information).
References:
Sarvi, Iraj;Gholizadeh, Mostafa;Izadyar, Mohammad [Catalysis Letters,2017,vol. 147,# 5,p. 1162 - 1171]
