2-(2-fluorophenyl)-1-phenylethan-1-one synthesis
9synthesis methods
- Product Name:2-(2-fluorophenyl)-1-phenylethan-1-one
- CAS Number:3826-47-9
- Molecular formula:C14H11FO
- Molecular Weight:214.23
Yield:3826-47-9 100%
Reaction Conditions:
Stage #1: (2-fluorophenyl)acetic acidwith thionyl chloride in dichloromethane;Inert atmosphere;Reflux;
Stage #2: benzenewith aluminum (III) chloride in dichloromethane at 0 - 20; for 5 h;Inert atmosphere;
References:
Mamboury, Mathias;Wang, Qian;Zhu, Jieping [Chemistry - A European Journal,2017,vol. 23,# 52,p. 12744 - 12748] Location in patent:supporting information
