一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 3,5-Dinitrobenzonitrile
4110-35-4

3,5-Dinitrobenzonitrile synthesis

6synthesis methods
In a well-ventilated hood, diphosgene (2 mL) was added dropwise to a cold (0–5 C°), stirred solution of 3,5-dinitrobenzamide (2.1 g, 10 mmol) in trimethyl phosphate (6.3 mL). The reaction mixture was then slowly heated to 60 C° for 5 min to ensure completion of the reaction and also to distil off any generated phosgene. After cooling in an ice/water bath, the reaction mixture was vigorously stirred and iced water (10 mL) was added to destroy any traces of phosgene or chloroformate. The precipitated solid product was collected by filtration, washed with water to eliminate traces of HCl and trimethyl phosphate, and air-dried; yield: 1.88 g (96%), mp 127–129 C°. Recrystallization from diisopropyl ether gave an analytically pure product, mp 130–131 C°.
The same authors also reported that alkyl, benzylic, aryl, and heteroaryl aldoximes bearing various functionalities could be readily converted to the corresponding nitriles using diphosgene in good yields of 82–96%.
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 83 percent / NH4Cl / methanol / 12 h / 55 - 60 °C
2: 7 percent / NaCl, NaOCl / dimethylsulfoxide; hexane; diethyl ether / 1.) 0 deg C, 1.5 h, 2.) room temp, 20 min.
3: NaN3, 2-nitropropane sodium salt / dimethylsulfoxide / 0.01 h / 17 °C

References:

Creary, Xavier [Journal of Organic Chemistry,1993,vol. 58,# 27,p. 7700 - 7708]

3,5-Dinitrobenzonitrile Related Search:

新平| 龙口市| 通城县| 龙南县| 宜兴市| 应城市| 进贤县| 旬阳县| 芦溪县| 嵊州市| 繁昌县| 乌海市| 阿荣旗| 嫩江县| 建始县| 金阳县| 梁河县| 琼海市| 赤峰市| 同仁县| 莱州市| 昌邑市| 白城市| 承德市| 玉门市| 木里| 偃师市| 彭州市| 连州市| 通辽市| 昭苏县| 诸暨市| 九江市| 顺平县| 屯门区| 余庆县| 平南县| 隆子县| 杭锦旗| 灌南县| 永登县|