ChemicalBook CAS DataBase List Isotretinoin

Isotretinoin synthesis

9synthesis methods

Product Name:Isotretinoin
CAS Number:4759-48-2
Molecular formula:C20H28O2
Molecular Weight:300.44

Preparation of isotretinoin in a single step from β-ionone and ethyl chloride are first reacted together after which the product is further reacted with triphenylphosphine to obtain Triphenyl salt. The Triphenyl salt is further reacted with cyclopentenone derivative to produce isotretinoin and its 8Z isomer. separate out the 8Z isomer and convert it to isotretinoin through isomerization with the help of nitric acid.

1-Penten-4-yn-3-ol, 3-methyl-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (1E)-

17974-59-3
0 suppliers
inquiry

4759-48-2
661 suppliers
$10.00/50mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 1.) ethylmagnesium bromide / 1.) THF, r.t., 1.5 h; 2.) THF, r.t., 1 h
2: 81 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 55 °C
3: 60 percent / LiAlH₄, titanium trichloride, triethylamine / tetrahydrofuran; diethyl ether / 0.5 h / 50 °C

References:

Solladie, G.;Berl, V. [Bulletin de la Societe Chimique de France,1993,vol. 130,p. 568 - 574]

59699-82-0 Synthesis

59699-82-0
6 suppliers
inquiry

4759-48-2
661 suppliers
$10.00/50mg

References

2H-Pyran-2-one, 5,6-dihydro-4-methyl-6-[(1E,3E)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-butadien-1-yl]-

43059-50-3
0 suppliers
inquiry

4759-48-2
661 suppliers
$10.00/50mg

References

81176-73-0
0 suppliers
inquiry

4759-48-2
661 suppliers
$10.00/50mg

References

20013-34-7
0 suppliers
inquiry

4759-48-2
661 suppliers
$10.00/50mg

302-79-4 Synthesis

302-79-4
759 suppliers
$5.00/100mg

References

Isotretinoin Related Search:

Folic acid Ethyl 2-(Chlorosulfonyl)acetate Dimethyl ether Dimethyl sulfone Dimethyl carbonate Ascorbic Acid Citric acid Dimethyl sulfoxide Menadione N,N-Dimethylaniline

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Isotretinoin synthesis

Isotretinoin Related Search: