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International Journal of Molecular Sciences

IF:5.6 Articles:13472

The International Journal of Molecular Sciences (ISSN 1422-0067) provides an advanced forum for chemistry, molecular physics (chemical physics and physical chemistry) and molecular biology. It publishes research articles, reviews, communications and short notes. Our aim is to encourage scientists to publish their theoretical and experimental results in as much detail as possible. Therefore, there is no restriction on the length of the papers or the number of electronics supplementary files. For articles with computational results, the full experimental details must be provided so that the results can be reproduced. Electronic files regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material (including animated pictures, videos, interactive Excel sheets, software executables and others).

Nuclear Binding Protein 2/Nesfatin-1 Affects Trophoblast Cell Fusion during Placental Development via the EGFR-PLCG1-CAMK4 Pathway

Published: 5 February 2024 DOI: 10.3390/ijms25031925
Qinyu Dang,?Yandi Zhu,?Yadi Zhang,?Zhuo Hu,?Yuchen Wei,?Zhaoyang Chen,?Xinyin Jiang,?Xiaxia Cai,?Huanling Yu

The Mechanism of Tigecycline Resistance in Acinetobacter baumannii under Sub-Minimal Inhibitory Concentrations of Tigecycline

Published: 2 February 2024 DOI: 10.3390/ijms25031819
Cunwei Liu, Jia Liu, Qinghui Lu, Ping Wang, Qinghua Zou

Bioinformatics and Experimental Validation for Identifying Biomarkers Associated with AMG510 (Sotorasib) Resistance in KRASG12C-Mutated Lung Adenocarcinoma

Published: 26 January 2024 DOI: 10.3390/ijms25031555
Peng Lin, Wei Cheng, Xin Qi, Pinglu Zhang, Jianshe Xiong, Jing Li

Establishment and Validation of Novel Prognostic Subtypes in Hepatocellular Carcinoma Based on Bile Acid Metabolism Gene Signatures Using Bulk and Single-Cell RNA-Seq Data

Published: 11 January 2024 DOI: 10.3390/ijms25020919
Yimo Qu, Xiaocheng Gong, Ziyuan Zhao, Zimei Zhang, Qian Zhang, Yuting Huang, Qingsong Xie, Yunfei Liu, Jinfen Wei, Hongli Du

Melatonin Alleviates Lipopolysaccharide-Induced Abnormal Pregnancy through MTNR1B Regulation of m6A

Published: 5 January 2024 DOI:
Shisu Zhao, Yanjun Dong, Yuanyuan Li, Zixu Wang, Yaoxing Chen, Yulan Dong

MP Allosterically Activates AMPK to Enhance ABCA1 Stability by Retarding the Calpain-Mediated Degradation Pathway.

Published: 8 December 2023 DOI: 10.3390/ijms242417280
Hui Li, Mingchao Wang, Kai Qu, Ruiming Xu, Haibo Zhu

Pharmacological Inhibition of PIP4K2 Potentiates Venetoclax-Induced Apoptosis in Acute Myeloid Leukemia

Published: 29 November 2023 DOI: 10.3390/ijms242316899
Keli Lima,?Maria Fernanda Lopes Carvalho,?Diego Antonio Pereira-Martins,?Frederico Lisboa Nogueira,?Lívia Bassani Lins de Miranda,?Mariane Cristina do Nascimento,?Rita de Cássia Cavaglieri,?Jan Jacob Schuringa,?Jo?o Agostinho Machado-Neto,?Eduardo Magalh?es Rego

The Novel Atypical Antipsychotic Lurasidone Affects Cytochrome P450 Expression in the Liver and Peripheral Blood Lymphocytes

Published: 27 November 2023 DOI: 10.3390/ijms242316796
Przemys?aw J Danek,?W?adys?awa A Daniel

Ethanol Extract of Radix Asteris Suppresses Osteoclast Differentiation and Alleviates Osteoporosis

Published: 20 November 2023 DOI: 10.3390/ijms242216526
Sung-Ju Lee,?Hyun Yang,?Seong Cheol Kim,?Dong Ryun Gu,?Jin Ah Ryuk,?Seon-A Jang,?Hyunil Ha

Cucurbitacin I Reverses Tumor-Associated Macrophage Polarization to Affect Cancer Cell Metastasis

Published: 2 November 2023 DOI: 10.3390/ijms242115920
Xiaocheng Gong,?Yunfei Liu,?Keying Liang,?Zixi Chen,?Ke Ding,?Li Qiu,?Jinfen Wei,?Hongli Du

A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)

Published: 20 October 2023 DOI: 10.3390/ijms242015389
Carmelo Pirri, Brasilina Caroccia, Andrea Angelini, Maria Piazza, Lucia Petrelli, Ilaria Caputo, Chiara Montemurro, Pietro Ruggieri, Raffaele De Caro, Carla Stecco

Inhibition of NLRP3 Inflammasome Activation by 3H-1,2-Dithiole-3-Thione: A Potential Therapeutic Approach for Psoriasis Treatment

Published: 31 August 2023 DOI: 10.3390/ijms241713528
Meng-Chieh Shih, Chia-Ling Li, En-Chih Liao, Chung-Yang Yen, Ling-Jung Yen, Kai-Chun Wang, Ling-Ying Lu, Ting-Yu Chou, Ying-Chin Chen, Sheng-Jie Yu

Betaxolol as a Potent Inhibitor of NDM-1-Positive E. coli That Synergistically Enhances the Anti-Inflammatory Effect in Combination with Meropenem

Published: 29 August 2023 DOI: 10.3390/ijms241713399
Jichao Sun, Shangjie Ren, Yaozu Yang, Xiaoting Li, Xiuying Zhang

Personalized CFTR Modulator Therapy for G85E and N1303K Homozygous Patients with Cystic Fibrosis

Published: 2 August 2023 DOI: 10.3390/ijms241512365
Simon Y Graeber, Anita Balázs, Niklas Ziegahn, Tihomir Rubil, Constanze Vitzthum, Linus Piehler, Marika Drescher, Kathrin Seidel, Alexander Rohrbach, Jobst R?hmel, Stephanie Thee, Julia Duerr, Marcus A Mall, Mirjam Stahl

Bacterial Outer Membrane Vesicles Loaded with Perhexiline Suppress Tumor Development by Regulating Tumor-Associated Macrophages Repolarization in a Synergistic Way

Published: 7 July 2023 DOI: 10.3390/ijms241311222
Shoujin Jiang, Wei Fu, Sijia Wang, Guanshu Zhu, Jufang Wang, Yi Ma

LncRNA H19 Regulates Breast Cancer DNA Damage Response and Sensitivity to PARP Inhibitors via Binding to ILF2

Published: 23 May 2023 DOI: 10.3390/ijms24119157
Junsong Zhao, Junchao Xu, Mingming Wu, Wei Wang, Miaomiao Wang, Leiyan Yang, Huayong Cai, Qiao Xu, Ceshi Chen, Peter E Lobie, Tao Zhu, Xinghua Han

Chemerin as an Inducer of β Cell Proliferation Mediates Mitochondrial Homeostasis and Promotes β Cell Mass Expansion

Published: 23 May 2023 DOI: 10.3390/ijms24119136
Min Li, Ruifan Zhang, Qian Ge, Lingzhi Yue, Dan Ma, Firas Khattab, Wenhua Xie, Yewei Cui, Patrick Gilon, Xueya Zhao, Xi Li, Rui Cheng

A Novel Time-Resolved Fluorescence Resonance Energy Transfer Assay for the Discovery of Small-Molecule Inhibitors of HIV-1 Tat-Regulated Transcription

Published: 23 May 2023 DOI: 10.3390/ijms24119139
Young Hyun Shin,?Dong-Eun Kim,?Kyung Lee Yu,?Chul Min Park,?Hong Gi Kim,?Kyung-Chang Kim,?Songmee Bae,?Cheol-Hee Yoon

A Potential ABA Analog to Increase Drought Tolerance in Arabidopsis thaliana

Published: 15 May 2023 DOI: 10.3390/ijms24108783
Ruiqi Liu, Guoyan Liang, Jiaxin Gong, Jiali Wang, Yanjie Zhang, Zhiqiang Hao, Guanglin Li

The Mechanism of Tigecycline Resistance in Acinetobacter baumannii Revealed by Proteomic and Genomic Analysis

Published: 12 May 2023 DOI: 10.3390/ijms24108652
Cunwei Liu, Lei Wang, Ping Wang, Di Xiao, Qinghua Zou

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