(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one
![(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one price.](/CAS/GIF/1032754-93-0.gif)
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- $43 - $5541
- Product name: (S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one
- CAS: 1032754-93-0
- MF: C23H30N8O3S
- MW: 498.6
- EINECS:
- MDL Number:MFCD20274520
- Synonyms:(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one;GNE 390;(S)-1-(4-((2-(2-aMinopyriMidin-5-yl)-7-Methyl-4-Morpholinothieno[3,2-d]pyriMidin-6-yl)Methyl)piperazin-1-yl)-2-hydroxypropan-1-one;GDC-0980 (RG7422);RG7422;Apitolisib (GDC-0980, RG7422);(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one GNE 390 GDC0980(RG7422);GNE 390 (S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one
75 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 2mg
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 2x5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 10mM(in1mLDMSO)
- 250mg
- 1.00g
- 1g
- 5.00g
- 5g
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95
- Packaging5mg
- Price$67
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95
- Packaging10mg
- Price$91
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95%
- Packaging1mg
- Price$43
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95
- Packaging2mg
- Price$51
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95
- Packaging25mg
- Price$148
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95
- Packaging50mg
- Price$227
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95
- Packaging100mg
- Price$359
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95%
- Packaging250mg
- Price$679
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035WP
- Product descriptionApitolisib 95%
- Packaging1g
- Price$1753
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21799
- Product descriptionApitolisib 98%
- Packaging1G
- Price$1350
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21799
- Product descriptionApitolisib 98%
- Packaging1G
- Price$1350
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21799
- Product descriptionApitolisib 98%
- Packaging250MG
- Price$450
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21799
- Product descriptionApitolisib 98%
- Packaging250MG
- Price$450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21799
- Product descriptionApitolisib 98%
- Packaging100MG
- Price$220
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21799
- Product descriptionApitolisib 98%
- Packaging100MG
- Price$220
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21799
- Product descriptionApitolisib 98%
- Packaging25MG
- Price$95
- Updated2026-05-25
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0035WP | Apitolisib 95 | 5mg | $67 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95 | 10mg | $91 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95% | 1mg | $43 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95 | 2mg | $51 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95 | 25mg | $148 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95 | 50mg | $227 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95 | 100mg | $359 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95% | 250mg | $679 | 2026-05-28 | Buy |
| aablocks | AA0035WP | Apitolisib 95% | 1g | $1753 | 2026-05-28 | Buy |
| ACHEMBLOCK | L21799 | Apitolisib 98% | 1G | $1350 | 2026-05-25 | Buy |
| ACHEMBLOCK | L21799 | Apitolisib 98% | 1G | $1350 | 2026-05-27 | Buy |
| ACHEMBLOCK | L21799 | Apitolisib 98% | 250MG | $450 | 2026-05-25 | Buy |
| ACHEMBLOCK | L21799 | Apitolisib 98% | 250MG | $450 | 2026-05-27 | Buy |
| ACHEMBLOCK | L21799 | Apitolisib 98% | 100MG | $220 | 2026-05-25 | Buy |
| ACHEMBLOCK | L21799 | Apitolisib 98% | 100MG | $220 | 2026-05-27 | Buy |
| ACHEMBLOCK | L21799 | Apitolisib 98% | 25MG | $95 | 2026-05-25 | Buy |
Properties
Melting point :>202°C (dec.)
Density :1.399
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.90±0.20(Predicted)
color :White to Light Yellow
Density :1.399
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.90±0.20(Predicted)
color :White to Light Yellow
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||||||||||||||||||
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Description
GDC-0980 is a potent inhibitor of class I phosphatidylinositol 3-kinase (PI3K) isoforms, with IC50 values of 5, 27, 7, and 14 nM for PI3Kα, β, δ, and γ, respectively, in cell-free assays. It also inhibits mTOR (Ki = 17 nM) but is inactive against a large panel of additional kinases. GDC-0980 induces cell cycle arrest or apoptosis in a range of cancer cell lines. It is effective in vivo, suppressing the growth of a number of tumor xenografts in mice and enhancing the antitumor activity of docetaxel in mice.Related product price
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Pictilisib (GDC-0941)
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GDC-0068
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![(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one](https://img.chemicalbook.com/ProductImageEN/2018-12/small/a8d9b725-3501-41e9-8ab0-ffa7fdbdccca.jpg){kind=small}
