2-Amino-5-nitrobenzoic acid synthesis
- Product Name:2-Amino-5-nitrobenzoic acid
- CAS Number:616-79-5
- Molecular formula:C7H6N2O4
- Molecular Weight:182.13
611-09-6
204 suppliers
$6.00/1g
616-79-5
360 suppliers
$8.00/5g
Yield:616-79-5 76.7%
Reaction Conditions:
with dihydrogen peroxide;sodium hydroxide at 10; for 3 h;
Steps:
1.2 (2) Preparation of 2-amino-5-nitrobenzoic acid (IV)
10 ° C, 3.3 g of 5-nitroisatin (III, 0.017 mol) was weighed,Slowly added to 100mL (1mol / L) sodium hydroxide solution,Stirring and dissolving completely, control reaction temperature about 10 ,100 mL (0.026 mol) of 3% hydrogen peroxide was slowly added dropwise,Stirring continued after 3h, with glacial acetic acid to adjust pH = 3 ~ 4,The crude product was filtered off, washed with a small amount of water and dried to give 2.4 g of yellow product (IV) in a yield of 76.7%
References:
Central South University;Jiang, Yuren;Wang, Xi;Xiao, Dandan;Du, Yangsen CN106146410, 2016, A Location in patent:Paragraph 0025; 0026
2516-96-3
457 suppliers
$6.00/25g
616-79-5
360 suppliers
$8.00/5g
943-14-6
180 suppliers
$17.50/1g
616-79-5
360 suppliers
$8.00/5g
121-92-6
603 suppliers
$6.00/25g
616-79-5
360 suppliers
$8.00/5g
121-92-6
603 suppliers
$6.00/25g
606-18-8
344 suppliers
$9.00/1g
1588-83-6
293 suppliers
$6.00/5g
616-79-5
360 suppliers
$8.00/5g