2-Amino-p-cresol synthesis
- Product Name:2-Amino-p-cresol
- CAS Number:95-84-1
- Molecular formula:C7H9NO
- Molecular Weight:123.15
119-33-5
32 suppliers
$23.00/25g
95-84-1
269 suppliers
$6.00/10g
Yield:95-84-1 100%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in methanol at 23; for 5 h;
Steps:
81
To a solution of 4-methyl-2-nitrophenol (1.0 g, 6.53 mmol) in methanol (10 mL) at 23° C. was added Pd/C (10 wt %, 400 mg), and the reaction mixture was deoxygenated under vacuum, then purged with hydrogen in a balloon. After stirring for 5 h, the reaction mixture was filtered through a pad of Celite and the Celite pad was rinsed with methanol (100 mL). The filtrate was concentrated in vacuo to yield 2-amino-4-methylphenol (803 mg, 100%).
References:
VICURON PHARMACEUTICALS INC. US2006/211603, 2006, A1 Location in patent:Page/Page column 68
1435-71-8
21 suppliers
inquiry
95-54-5
537 suppliers
$9.00/1g
95-84-1
269 suppliers
$6.00/10g
2440-22-4
463 suppliers
$8.00/25g
54659-85-7
0 suppliers
inquiry
1435-71-8
21 suppliers
inquiry
95-54-5
537 suppliers
$9.00/1g
95-84-1
269 suppliers
$6.00/10g
54659-85-7
0 suppliers
inquiry
952-47-6
47 suppliers
$45.00/50mg
95-84-1
269 suppliers
$6.00/10g