ChemicalBook CAS DataBase List Cyclobutanecarboxylic acid

Cyclobutanecarboxylic acid synthesis

11synthesis methods

Product Name:Cyclobutanecarboxylic acid
CAS Number:3721-95-7
Molecular formula:C5H8O2
Molecular Weight:100.12

Cyclobutanecarboxylic acid synthesis: Put 1,1-Cyclobutanedicarboxylic acid into a distillation device for heating, decarboxylate at about 160°C to release carbon dioxide, then heat for distillation, collect 189-195°C fractions as crude product, and re-distill to obtain the finished product cyclobutanecarboxylic acid. Yield 86%-91%.

74-85-1
113 suppliers
$79.00/11l

79-10-7 Synthesis

79-10-7
735 suppliers
$20.16/100 mL

3721-95-7
425 suppliers
$7.00/5g

Yield:3721-95-7 97%

Reaction Conditions:

in dichloromethane at -30 - -20; for 3 h;UV-irradiation;Temperature;

Steps:

1 Example 3
72 g acrylic acid into four 500ml glass bottle, 500 g of methylene chloride, topical acetone - dry ice bath cooled to -70 ~ -50 After slowly ethylene gas, was passed rate 137ml / min 4 common hours into 41 g, with violet 450Wfor outer light catalytic high pressure mercury lamp in the control sample GC after the reaction was complete disappearance of starting material acrylic acid to obtain a reaction solution, stopping the flow of ethylenealkenyl gas, turn off the UV lamp, the reaction mixture was distilled atmospheric whole the solvent was removed to give 99.8 g red-brown liquid, by GC analysis, cyclobutylacid purity 98.6%; red-brown liquid was distilled under reduced pressure, vacuum distillation pressure is -0.07 MPa, a temperature of 90 deg.] C; to givea colorless to pale The yellow finished product was 97.1 g of a cyclobutyl formic acid liquid with a GC purity of 99.5% and a yield of 97%

References:

Changzhou Woteng Chemical Technology Co., Ltd.;Wei Xinghong;Sun Fuqiang;Li Honggong;Wang Mingfeng CN107805197, 2018, A Location in patent:Paragraph 0009; 0010-0012

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4415-82-1 Synthesis