p-Toluic acid synthesis
- Product Name:p-Toluic acid
- CAS Number:99-94-5
- Molecular formula:C8H8O2
- Molecular Weight:136.15
122-00-9
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99-94-5
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$9.00/1g
Yield:99-94-5 99%
Reaction Conditions:
with oxygen;copper(II) nitrate in acetonitrile at 120; under 4500.45 Torr; for 10 h;
Steps:
27 Example 27
In a 15 mL PTFE-lined reactor, 0.5 mmol of 4-methylacetophenone was added.Weigh 0.1 mmol of copper nitrate as a catalyst,And adding 2mL solvent acetonitrile (4-methyl acetophenone concentration is 0.25mol / L),The oxygen pressure is increased to 0.6 MPa, the temperature is raised to 120 ° C, and the reaction is stirred for 10 hours. After the reaction is completed,The product was detected by gas chromatography-mass spectrometry and the product 4-methylbenzoic acid mass spectrum was identical to the standard mass spectrum.The conversion of the substrate by gas chromatography and the yield of the product 4-methylbenzoic acid are shown in Table 1.
References:
CN108002968,2018,A Location in patent:Paragraph 0109; 0110
536-50-5
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99-94-5
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$9.00/1g
106-43-4
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99-94-5
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1218-89-9
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99-94-5
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