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6893-26-1

中文名稱 D-谷氨酸
英文名稱 D(-)-Glutamic acid
CAS 6893-26-1
EINECS 編號 230-000-8
分子式 C5H9NO4
MDL 編號 MFCD00063112
分子量 147.13
MOL 文件 6893-26-1.mol
更新日期 2026/05/25 10:05:16
6893-26-1 結(jié)構(gòu)式 6893-26-1 結(jié)構(gòu)式

基本信息

中文別名
D-谷氨酸
D-麩胺酸
D-2-氨基戊二酸
D-麩氨酸
D-麩質(zhì)酸
D-谷氨酸(試劑)
D-Α-氨基戊二酸,D-Α-AMINOPENTANEDIOIC ACID
D-谷氨酸/Α-氨基戊二酸
D-谷氨酸, 99+%
英文別名
-GLU
NSC 77686
H-D-GLU-OH
d-glutamic
D-Glutamate
d-glutamicaci
D-Glutaminsure
D-GLUTAMIC ACID
(R)-GLUTAMIC ACID
GLUTAMIC ACID, D-
D-Glutaminic acid
(2R)-GlutaMic Acid
D-GLUCURONOLACTONE
D-(-)-GLUTAMIC ACID
D-GLUTAMIC ACID, 99+%
D-GlutaMic acid, 95+%
D-α-AMinoglutaric acid
D-2-AMINOGLUTARIC ACID
(R)-2-AMINOGLUTARIC ACID
D-GLUTAMIC ACID extrapure
(2R)-2-Aminoglutaric acid
D-ALPHA-AMINOGLUTARIC ACID
D-2-AMINOPENTANEDIOIC ACID
[R]-2-AMINOPENTANEDIOIC ACID
D(-)-GlutaMic acid, 99+% 5GR
D(-)-GlutaMic acid, 99+% 25GR
(2R)-2-aminopentanedioic acid
D-1-AMinopropane-1,3-dicarboxylic acid
(R)-1-AMINOPROPANE-1,3-DICARBOXYLIC ACID
(R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(-)-1-Aminopropane-1,3-dicarboxylic acid
所屬類別
生物化學(xué)品: 生化試劑: 氨基酸及其衍生物

物理化學(xué)性質(zhì)

外觀性狀白色結(jié)晶或結(jié)晶性粉末;溶于水,微溶于乙醇,不溶于乙醚;比旋光度[α]20D-30.5°(0.5-2mg/ml,6mol/L HCl),LD50(人,靜脈) 117mg/kg。
熔點(diǎn)200-202 °C (subl.)(lit.)
熔點(diǎn)200-202 °C (subl.)(lit.)
比旋光度-31.3 º (c=10, 2 N HCl)
沸點(diǎn)267.21°C (rough estimate)
密度1.5380
折射率1.4210 (estimate)
儲存條件Keep in dark place,Sealed in dry,Room Temperature
儲存條件Store at RT.
溶解度可微溶于水
酸度系數(shù)(pKa)pK1:2.162(+1);pK2:4.272(0);pK3:9.358(-1) (25°C)
形態(tài)粉末
顏色白色至灰白色
水溶解性7 g/L (20 ºC)
Merck14,4469
BRN1723800
InChI1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChIKeyWHUUTDBJXJRKMK-GSVOUGTGSA-N
SMILESN[C@H](CCC(O)=O)C(O)=O
LogP-0.969 (est)
CAS 數(shù)據(jù)庫6893-26-1(CAS DataBase Reference)
NIST化學(xué)物質(zhì)信息D-Glutamic acid(6893-26-1)
EPA化學(xué)物質(zhì)信息D-Glutamic acid (6893-26-1)

安全數(shù)據(jù)

危險(xiǎn)性符號(GHS)有害 (GHS07)
GHS07
警示詞警告
危險(xiǎn)性描述H315-H319
危險(xiǎn)品標(biāo)志Xi
危險(xiǎn)類別碼36/37/38
安全說明24/25-36-26
安全說明S24/25
WGK Germany3
WGK Germany3
TSCAYes
海關(guān)編碼29224210
存儲類別11 - Combustible Solids

應(yīng)用領(lǐng)域

用途一
用于生化研究。
用途二
氨基酸類藥。
參考質(zhì)量標(biāo)準(zhǔn)
比旋光度[α]20D-31°--33°;紙層析合格。

制備方法

方法一
以乙酰-DL-谷氨酸為原料,經(jīng)?;柑幚砗笕-型,精制、干燥得產(chǎn)品。

化學(xué)品安全說明書(MSDS)

D-谷氨酸價(jià)格(試劑級)
報(bào)價(jià)日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價(jià)格
2026/03/03A14191D-谷氨酸, 99+%
D-Glutamic acid, 99+%
6893-26-1100g3336元
2026/03/0322789D-谷氨酸
D(-)-Glutamic acid, 99+%, Thermo Scientific Chemicals
6893-26-1100g4176元
2025/12/22HY-100805D-谷氨酸
D-Glutamic acid
6893-26-1500mg250元

常見問題列表

生物活性
D-glutamic acid是L-glutamic acid的對映異構(gòu)體,廣泛用于藥物和食品中。
靶點(diǎn)

Human Endogenous Metabolite

體外研究

Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.

體內(nèi)研究

D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.

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